DW Insights & Inquiries
IGM should be considered in inflammatory dermatoses of the breast in women of reproductive age. There are an increasing number of reports of IGM accompanied by extramammary manifestations, notably erythema nodosum.
MEK inhibition may be a new therapeutic pathway to treat disorders demonstrating focal acantholytic dyskeratosis, including Darier disease and Grover disease.
Retinoids are standard therapy for patients with severe ichthyoses and disorders of keratinization. The promise of a safe and effective topical isotretinoin would be a welcome therapeutic advance.
Terra firma-forme dermatosis is diagnosed by a simple alcohol wipe. Recognition of this disorder may ease fears and embarrassment and avoid unnecessary diagnostic tests.
Lipoid proteinosis was described almost a century ago. Genetic discoveries have yet to translate into precise therapeutic interventions. Acitretin remains the systemic treatment of choice.
Rapidly progressing interstitial lung disease and pneumomediastinum are potentially life-threatening complications of anti-MDA5-postiive dermatomyositis. Dyspneic patients with this disease mandate urgent assessment.
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