Dermatology World Insights and Inquiries

Histamine-1 receptor blockers are routinely used to treat the pruritus of AD, although histamine does not seem to play a role in AD through the histamine-1 receptor.

Prostaglandins were the rage when I started medical school in 1975; their role in inflammatory dermatoses was considered of paramount importance throughout my residency in the early 1980s. 

The clinical variability of ND runs the spectrum from urticarial lesions to Sweet syndrome, pyoderma gangrenosum, to resembling necrotizing fasciitis.

The challenges of treating severe psoriasis with the Goeckerman regimen, PUVA, methotrexate, etc. made the concept of a PASI 100 virtually unfathomable. 

Patterned skin injury can raise the specter of non-accidental trauma. Striking examples of patterned skin injury have emerged among adolescents that share certain features...

At an early age I learned of the bidirectional nature of stress and acne — stress aggravates acne, while acne exacerbates stress.

Of all the cutaneous entities I have never thought much about, cherry angiomas top the list.

Are you a creature of habit when it comes checking laboratory tests for certain prescriptions? I am. 

After using a drug for years, physicians become comfortable with the benefits and risks of the frequently prescribed agent. I have utilized ustekinumab extensively ...

PML is a nightmare. For any dermatologist seeing patients with autoimmune diseases, HIV, lymphoproliferative disorders, or who are on immunosuppressive medications, PML is a ‘sword of Damocles’ ...