DW Insights & Inquiries
Use terms that emphasize the relationship between skin disease and monoclonal gammopathy; aid in collaborative multidisciplinary discussions; and provide a rationale for treating the underlying pathogenic clone.
Pellagra due to niacin deficiency still exists as a primary disorder in less developed countries and as a secondary disorder in industrialized countries.
Trichobacteriosis is the more accurate name for the corynebacterial infection with the misnomer of trichomycosis axillaris.
Lipid vacuoles (Jordans’ anomaly) in white blood cells in patients with ichthyotic disorders (resembling nonbullous congenital erythroderma or the erythrokeratodermas) are indicative — but not pathognomonic — of the Chanarin-Dorfman syndrome.
Eccrine mucin-producing sweat gland carcinomas are low-grade malignancies that rarely metastasize. They are characterized by mucin and neuroendocrine markers. Immunostaining for insulinoma-associated protein 1 helps to secure the diagnosis.
Squamoid eccrine ductal carcinomas may be highly aggressive malignancies characteristically observed on the head and neck of older men. Biopsies must be deep enough to ensure that these lesions are not diagnosed as squamous cell carcinomas.
To improve the practice of dermatology, while being stimulating, practical, thought-provoking, and enlightening by offering critical perspectives on current dermatologic literature meant to be used in the clinic today and in the future.
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