DW Insights & Inquiries
The IL-6 inhibitor tocilizumab may have a therapeutic role in cases of recalcitrant morphea.
Anifrolumab, a monoclonal antibody that blocks type 1 interferon signaling, has been increasingly reported as an effective treatment in patients with recalcitrant chronic cutaneous lupus erythematosus.
Merkel cell carcinoma may be associated with several paraneoplastic phenomena, including the syndrome of inappropriate anti-diuretic hormone secretion, ectopic Cushing syndrome, and others.
Much remains to be learned about this enigmatic lesion and its relationship to other CD34-positive lesions such as the plaque-like CD34-positive dermal fibroma and the fibroblastic connective tissue nevus.
Dilated, depressed frontal veins are a clinical sign of frontal fibrosing alopecia.
Nail clippings demonstrating melanocyte remnants serve as a triage for those patients who should have a nail matrix biopsy performed to evaluate for a nail unit melanoma.
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The American Academy of Dermatology gratefully acknowledges support from Bristol Myers Squibb.