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DW Insights & Inquiries

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Alaskapox: The beat goes on

Alaskapox is a newly recognized infectious disease due to an Orthopoxvirus likely transmitted by small mammals. Most cases are mild, but a fatal case has been reported in a presumably immunosuppressed host.

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Caveat mTOR revisited: Neurofibromatosis

Targeting the MAPK/ERK and PI3K/AKT/mTOR pathway has led to the use of topical sirolimus for neurofibromas and oral selumetinib for children with plexiform neurofibromas.

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Short anagen syndrome: The long and short of it

SAS is an underrecognized disorder usually observed in children and typically resolves after puberty. It may be accompanied by psychological distress. Topical minoxidil and oral biotin may help therapeutically.

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Early-onset hypertension and capillary malformations

Patients presenting with extensive capillary malformations (port wine stains) on the trunk and extremities should be routinely screened for early-onset hypertension.

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Senile gluteal dermatosis

Senile gluteal dermatosis is an underrecognized frictional dermatosis seen mostly in thin, elderly patients. But the term “senile” is getting old and should be retired.

Card image for DWII on multiple neonatal staphylococcal cold abscesses of the large folds
Neonatal staphylococcal cold abscesses of the large folds

Healthy neonates presenting with cold abscesses in skin folds and growing methicillin-sensitive staph on culture may have this disorder. With appropriate treatment, it will not have any untoward sequelae.

The mission of DW Insights & Inquiries

To improve the practice of dermatology, while being stimulating, practical, thought-provoking, and enlightening by offering critical perspectives on current dermatologic literature meant to be used in the clinic today and in the future.

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Explore Dermatology World Insights and Inquiries clinical topics by practice focus, condition, and medical journal source.

All content solely developed by the American Academy of Dermatology

The American Academy of Dermatology gratefully acknowledges support from Bristol Myers Squibb.

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