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DW Insights & Inquiries

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Digging deeper into lupus erythematosus panniculitis

Lupus erythematosus panniculitis (LEP) has a storied history. Histologically, LEP variably displays a lymphoplasmacytic lobular panniculitis with epidermal and dermal changes of lupus, hyaline fat necrosis, and lymphoid follicles.

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Staphylococcal scalded skin syndrome

What can possibly be new about SSSS? Four aspects – 1) epidemiology; 2) causation; 3) the clinical spectrum; and 4) therapeutic approach.

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Nailing down the treatment for ungual melanoma in situ

Increasing evidence demonstrates the favorability of en bloc excision of the nail unit as treatment over amputation. This message needs to be communicated to colleagues in all specialties involved with managing ungual melanomas.

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LIDA* rose the insulin requirement

Recognizing localized insulin-derived amyloidosis (LIDA), a rare complication of insulin, is essential because of its potential havoc on glycemic control. Surgical excision of LIDA offers optimal management.

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Keeping an eye on melanoma

CAR is defined as an autoantibody-driven retinal degeneration that is not caused by tumor metastasis. The prevailing hypothesis is that antiretinal antibodies in high titers penetrate the retina, affecting function of the target antigens.

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Netherton syndrome: From apex to nether

NS (OMIM 256500) is a rare autosomal recessive disorder, due to germline mutation of SPINK5, affecting one in 100,000 to 200,000 live births.


About DW Insights & Inquiries

The goal of this website is to improve the practice of dermatology, while being stimulating, practical, thought-provoking, and enlightening. Perspectives on current dermatologic literature are offered that are meant to be used in the clinic.

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Explore Dermatology World Insights and Inquiries clinical topics by practice focus, condition, and medical journal source.

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The American Academy of Dermatology gratefully acknowledges support from Incyte Dermatology.

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