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DW Insights & Inquiries

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Card image for DWII on topical isotretinoin for ichthyoses
Topical isotretinoin for ichthyoses

Retinoids are standard therapy for patients with severe ichthyoses and disorders of keratinization. The promise of a safe and effective topical isotretinoin would be a welcome therapeutic advance.

Image for DWII of terra firma-forme dermatosis
Terra firma-forme dermatosis

Terra firma-forme dermatosis is diagnosed by a simple alcohol wipe. Recognition of this disorder may ease fears and embarrassment and avoid unnecessary diagnostic tests.

Image for DWII of lipoid proteinosis
Lipoid proteinosis’s cry for therapeutic intervention

Lipoid proteinosis was described almost a century ago. Genetic discoveries have yet to translate into precise therapeutic interventions. Acitretin remains the systemic treatment of choice.

Card illustration for The breathless complications of anti-MDA-5-positive dermatomyositis
Complications of anti-MDA-5-positive dermatomyositis

Rapidly progressing interstitial lung disease and pneumomediastinum are potentially life-threatening complications of anti-MDA5-postiive dermatomyositis. Dyspneic patients with this disease mandate urgent assessment.

Image for DWII on heat shock protein inhibition
Heat shock protein inhibition

Heat shock protein inhibition is a novel approach that may prove valuable for dermatologists treating inflammatory, autoimmune, bullous, and oncologic diseases.

Image for DWII of atopic dermatitis
Homing in on hornerin

Maintaining the skin barrier is crucial in managing patients with atopic dermatitis. Research on newly discovered proteins in the stratum corneum, such as hornerin, may lead to novel therapeutic interventions.


The mission of DW Insights & Inquiries

To improve the practice of dermatology, while being stimulating, practical, thought-provoking, and enlightening by offering critical perspectives on current dermatologic literature meant to be used in the clinic today and in the future.

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