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DW Insights & Inquiries

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Card image for DWII of sclerosing lymphangitis of the penis
Reassuring patients with sclerosing lymphangitis of penis

Sclerosing lymphangitis of the penis may be anxiety-provoking but is a self-limited disorder that characteristically resolves within weeks without residual complications.

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Vasculitis on the run

Vigorous exercise may induce a self-limited cutaneous leukocytoclastic vasculitis, including the recently described bilateral lower extremity inflammatory lymphedema.

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Fire ant stings: The therapeutic potential of solenopsin

The fire ant venom, solenopsin (and its analogs), has demonstrated anti-inflammatory efficacy in mouse models of atopic dermatitis and psoriasis. Further research is necessary to determine its potential in human disease.

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Pathway to reducing medical errors

Although the overall error rate may be low, there are specific areas and opportunities to further reduce errors in the diagnostic pathway.

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Advances in pruritus therapeutics: It’s Greek to us

Recent studies on the oral kappa-opioid receptor difelikefalin demonstrate benefit in treating pruritus in several dermatoses such as atopic dermatitis, notalgia paresthetica, and chronic kidney disease.

Card illustration for CXCR4 antagonist therapy
CXCR4 antagonist therapy based on a WHIM syndrome

Advances in understanding the pathomechanisms of WHIM syndrome are the prelude to treating this syndrome — and other diseases — with CXCR4 antagonists.


The mission of DW Insights & Inquiries

To improve the practice of dermatology, while being stimulating, practical, thought-provoking, and enlightening by offering critical perspectives on current dermatologic literature meant to be used in the clinic today and in the future.

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