U073 - Genodermatoses Update
Monday, February 19; 7:30 AM - 8:30 AM
Following this course, the attendee should be able to:
- Formulate a framework for understanding autoinflammatory skin disease and the rationale for targeted intervention of specific pathways.
- Recognize targeted therapies for autoinflammatory conditions based on pathways involved.
- Describe clinical features of monogenic autoinflammatory syndromes of the IL-1 cytokine family, proteasome, and interferonopathies.
This session will provide an overview of monogenic autoinflammatory syndromes described in the last several years with an emphasis on skin diseases with important systemic manifestations. Topics will include new autoinflammatory and immunodeficiency diseases, among others. Recent advances in the monogenic basis of these conditions, as well as the underlying pathophysiologic pathways responsible for the skin phenotypes will be discussed. These mechanisms provide new insight into our understanding of cutaneous infection, autoinflammation, and granuloma formation in both rare and common disease.
- Pichard, Dominique C., MD: no financial relationships exist with commercial interests.
Monday, February 19
Dr. Pichard / Monogenic autoinflammatory syndromes