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PAPA, PASH, and PAPASH-Syndromes, SAPHO, and Acne: Skin, Bones, and Inflammation
Friday, March 21
1:00 PM - 3:00 PM
Gerd Plewig, MD
Following this course, the attendee should be able to:
- Recognize how autoinflammatory diseases, acne, arthritis, and pyoderma gangrenosum interact
- Describe how interleukin-one receptor antagonists immediately improve pyoderma gangrenosum
Hereditary and acquired inflammatory signs and symptoms affecting skin, bones, lungs, and gut may be seen in PAPA syndrome, PASH syndrome and PAPASH syndrome (pyoderma gangrenosum, acne, and suppurativa hidradenitis), SAPHO syndrome (synovitis, acne, pustulosis palmoplantaris, hyperostosis, and osteitis). The session focuses on important knowledge of proteins interacting with pyrin. Genetic testing is available for the above mentioned syndromes.
Therapeutic recommendations are given.