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Session Information

FOC U037 - Better Understanding of Basic Science in Dermatology from Bench to Bedside

Open admission to eligible categories, no tuition or ticket


Date: Sunday, March 03

CME Credits: 1.00

Location: Room B121/122

Time: 7:00 AM - 8:00 AM

Director: Rachael Clark, MD, PhD, FAAD

Learning Objectives:
Following this course, the attendee should be able to:

  • Distinguish the relative contributions of epithelial barrier dysfunction and immune cells in atopic dermatitis
  • Recognize how IL-17 contributes to psoriasis
  • Recognize how a better understanding of skin T cell responses may lead to better vaccines

Advances in the understanding of atopic dermatitis and psoriasis have led to novel therapies and new insights into human immune responses in the skin. We will discuss the critical interplay of the immune system and epithelial barrier dysfunction in atopic dermatitis and novel work showing a definitive role for IL-17 in the pathogenesis of psoriasis. We will review recent studies regarding T cell protection of barrier tissues and how these findings might lead to better vaccines. Lastly, we will discuss the newly described subset of T cells that produce IL-9 and emerging their role in human immune responses.