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Session Information

FRM F119 - PAPA-Syndrome, SAPHO, and Acne: Skin, and Bones and Inflammation

Open admission to eligible categories, no tuition or ticket


Date: Monday, March 04

CME Credits: 2.00

Location: Room B112/113

Time: 1:00 PM - 3:00 PM

Director: Gerd Plewig, MD

Learning Objectives:
Following this course, the attendee should be able to:

  • Recognize how autoinflammatory diseases, acne, arthritis, and pyoderma gangrenosum interact
  • Describe how interleukin-1 receptor antagonists immediately improve pyoderma gangrenosum
  • Identify which laboratory tests are required and which treatment options are available

Hereditary and acquired inflammatory signs and symptoms affecting skin, bones, lungs, and gut may be seen in PAPA syndrome (pyogenic arthritis, pyoderma gangrenosum, and acne), PASH (pyoderma gangrenosum, acne and suppurative hidradenitis), SAPHO syndrome (synovitis, acne, pustulosis palmoplantaris, hyperostosis, and osteitis), cryopyrinopathies, and other autoinflammatory syndromes. This session focuses on important knowledge of proteins interacting with pyrin. Furthermore, acne inversa (alias hidradenitis suppurativa) is associated with Crohn's disease and ulcerative colitis.