Psoriasis: Recommendations for vitamin D analogues

  • Indication: Plaque-type psoriasis
  • Contraindications/adverse reactions:
    • Irritation in lesional and perilesional skin that is transient
    • Reversible elevation of serum calcium--more likely to occur patients treated with greater than 100g/wk.
    • Causes photosensitivity, but no contraindications to combining with UVB phototherapy;when using combination calcipotriene/betamethasone, the side effects of high-potency topical corticosteroids including HPA axis suppression, skin atrophy, among others (see above) may occasionally occur.

Level of Evidence: I Strength of Recommendation: A


Navigate section 3 of the psoriasis guideline: Topical therapies

Citation note

When referencing this guideline in a publication, please use the following citation: Menter A, Korman NJ, Elmets CA, Feldman SR, Gelfand JM, Gordon KB,et al. Guidelines of care for the management of psoriasis and psoriatic arthritis. Section 3. Guidelines of care for the management and treatment of psoriasis with topical therapies. J Am Acad Dermatol. 2009 Apr;60(4):643-59.



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