Psoriasis: Recommendations for salicylic acid

  • Indications: No specific FDA indication.
  • Contraindications/adverse reactions: 
    • Do not combine salicylic acid with other salicylate drugs.
    • Systemic absorption, although rare, can occur, especially when applied to more than 20% of BSA or in patients with abnormal hepatic or renal function. 
    • Salicylic acid decreases the efficacy of UVB phototherapy because of a filtering effect and should not be used before UVB phototherapy.


Navigate section 3 of the psoriasis guideline: Topical therapies

Citation note

When referencing this guideline in a publication, please use the following citation: Menter A, Korman NJ, Elmets CA, Feldman SR, Gelfand JM, Gordon KB,et al. Guidelines of care for the management of psoriasis and psoriatic arthritis. Section 3. Guidelines of care for the management and treatment of psoriasis with topical therapies. J Am Acad Dermatol. 2009 Apr;60(4):643-59.