Psoriasis: Recommendations for oral PUVA photochemotherapy

  • Systemic psoralen plus ultraviolet A is indicated for adults with generalized psoriasis who are resistant to topical therapy.
  • PUVA treatment is contraindicate in patients with known lupus erythematosus, porphyria, or xeroderma pigmentosum.  

Level of Evidence: I  Strength of Recommendation: A 

  • Combination of PUVA and topical agents

Level of Evidence: I  Strength of Recommendation: A

  • Combination of PUVA and systemic agents

Level of Evidence: II  Strength of Recommendation: B

Navigate section 5 of the psoriasis guideline: Phototherapy and photochemotherapy

Citation note

When referencing this guideline in a publication, please use the following citation: Menter A, Korman NJ, Elmets CA, Feldman SR, Gelfand JM, Gordon KB, et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 5. Guidelines of care for the treatment of psoriasis with phototherapy and photochemotherapy. J Am Acad Dermatol. 2010 Jan;62(1):114-35. 


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