Atopic dermatits: Recommendations for the use of systemic antimicrobials

  • The use of systemic antibiotics in the treatment of non-infected AD is not recommended. 
    Strength of Recommendation: B Level of Evidence: II

  • Systemic antibiotics are appropriate and can be recommended for use in patients with clinical evidence of bacterial infections in addition to standard and appropriate treatments for AD disease itself (which may include the concurrent use of topical corticosteroids).
    Strength of Recommendation: A Level of Evidence: II
    (Strength of Recommendation: C Level of Evidence: III)
  • Systemic antiviral agents should be used for the treatment of eczema herpeticum.
    Strength of Recommendation: C Level of Evidence: II

Navigate section 3 of the AD guideline: Phototherapy and systemic agents  

Citation note

When referencing this guideline in a publication, please use the following citation: Sidbury R, Davis DM, Cohen DE, Cordoro KM, Berger TG, Bergman JN, et al. Guidelines of care for the management of atopic dermatitis: section 3. Management and treatment with phototherapy and systemic agents. J Am Acad Dermatol. 2014 Aug;71(2):327-49. 


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