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Twenty-two different AD-specific, dermatology-specific, and generic scales were identified that measure quality of life and other psychological outcomes in patients with atopic dermatitis.43,58-66 These scales have been used to assess the impact of the disease and the effects of interventions, as well as to make comparisons with the impact of other disorders. Careful consideration of the scale properties should occur prior to use, including validity (content, construct, concurrent, discriminative), reliability (test-retest and internal consistency), responsiveness to change, and minimal clinically important difference.58,60,67,68 In clinical trials, the most commonly used scale is the Children's Dermatology Life Quality Index (CDLQI), followed by the Dermatitis Family Impact (DFI), the Dermatology Life Quality Index (DLQI), and the Infant's Dermatology Life Quality Index.43 But these scales were not generally designed for use in routine clinical practice.69